01 - Heat a large skillet over medium-high heat. Add the ground beef, salt, pepper, smoked paprika, and garlic powder. Break up the meat with a spoon and cook until browned throughout, approximately 7-8 minutes. Drain any excess fat before removing from heat.
02 - While the beef cooks, whisk together the mayonnaise, ketchup, mustard, pickle relish, apple cider vinegar, smoked paprika, salt, and pepper in a small bowl until smooth and fully combined. Set aside until serving.
03 - Divide the chopped romaine lettuce evenly among four large serving bowls. Arrange equal portions of the cooked ground beef, cherry tomatoes, shredded cheddar cheese, red onion, pickle slices, and diced avocado over the lettuce in each bowl.
04 - Drizzle the prepared burger sauce generously over each bowl. Serve immediately while the beef is still warm.