01 - Preheat the oven to 425°F. Line a large baking sheet with parchment paper or lightly grease with nonstick spray.
02 - In a large mixing bowl, whisk together flour, water, garlic powder, smoked paprika, onion powder, salt, and black pepper until smooth.
03 - Add the cauliflower florets to the batter and toss well to coat evenly on all sides.
04 - Place panko breadcrumbs in a shallow dish. Dip each batter-coated floret into the panko, pressing gently to adhere the crumbs.
05 - Arrange breaded florets in a single layer on the prepared baking sheet. Bake for 20 minutes, flipping halfway through for even browning.
06 - While cauliflower bakes, combine hot sauce, melted butter, and honey (if using) in a small saucepan over low heat. Stir until warmed and well combined.
07 - Remove cauliflower from the oven after 20 minutes. Gently toss the baked florets with the Buffalo sauce until evenly coated.
08 - Return the sauce-coated florets to the baking sheet and bake for an additional 10 minutes until crispy and slightly caramelized.
09 - Serve hot with celery sticks, carrot sticks, and your choice of ranch or blue cheese dressing for dipping.