01 - Pat shrimp dry with paper towels, then season evenly with kosher salt and black pepper.
02 - Arrange three shallow bowls. Combine flour, cornstarch, garlic powder, and smoked paprika in the first bowl. Beat eggs in the second bowl. Place panko breadcrumbs in the third bowl.
03 - Dredge each shrimp in the flour mixture, shaking off excess. Dip into beaten eggs, then press firmly into panko to coat thoroughly.
04 - Pour 2 inches of vegetable oil into a deep skillet or Dutch oven. Heat to 350°F, maintaining temperature throughout frying.
05 - Fry shrimp in batches for 2–3 minutes, turning once halfway through, until golden brown and crispy. Remove and drain on paper towels.
06 - In a small saucepan over low heat, melt butter with honey, hot sauce, and red pepper flakes. Whisk until fully combined and heated through, about 1–2 minutes.
07 - Transfer fried shrimp to a bowl. Pour hot honey glaze over shrimp and toss until evenly coated. Serve immediately, garnished with fresh chives or parsley and lemon wedges.